Title : Cytokine-dependent modification of IL-12p70 and IL-23 balance in dendritic cells by ligand activation of Valpha24 invariant NKT cells.

Pub. Date : 2009 Jul 1

PMID : 19542431






1 Functional Relationships(s)
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1 This study demonstrates that the activation of human iNKT cells by their specific ligand alpha-galactosylceramide enhances IL-12p70 while inhibiting the IL-23 production by monocyte-derived dendritic cells, and in turn down-regulating the IL-17 production by memory CD4(+) Th cells. alpha-galactosylceramide interleukin 17A Homo sapiens