Pub. Date : 2009 Sep
PMID : 19540550
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, Cu(2+) release in Cu and Cu-C nanoparticle suspensions caused 40% and 45% of AChE activity reduction, respectively. | Copper | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | AChE inhibition by bulk Cu and activated carbon particles was also measured for comparison, showing that the inhibition by bulk particles was lower than their counterpart nanoparticles. | Copper | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | For bulk Cu particles, AChE inhibition was primarily caused by dissolved ions, but mainly by adsorption for activated carbon. | Copper | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | AChE inhibition by Cu, Cu-C, MWCNT and SWCNT had dose-response relationships, and their median inhibitory concentrations (IC(50)) were 4, 17, 156 and 96mgL(-1), respectively, showing that these nanoparticles may have neurotoxicity and AChE may have potential to be used as a biomarker for nanoparticles. | Copper | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 5 | AChE inhibition by Cu, Cu-C, MWCNT and SWCNT had dose-response relationships, and their median inhibitory concentrations (IC(50)) were 4, 17, 156 and 96mgL(-1), respectively, showing that these nanoparticles may have neurotoxicity and AChE may have potential to be used as a biomarker for nanoparticles. | Copper | acetylcholinesterase (Cartwright blood group) | Homo sapiens |