Title : Phosphorylation-dependent autoinhibition of myosin light chain phosphatase accounts for Ca2+ sensitization force of smooth muscle contraction.

Pub. Date : 2009 Aug 7

PMID : 19531490






1 Functional Relationships(s)
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Protein Name
Organism
1 GST-MYPT1 fragments induced a contraction of beta-escin-permeabilized ileum SM at constant pCa 6.3 (EC(50) = 2 microm), which was eliminated by Ala substitution of the fragment at Thr-696 or by ROCK inhibitors or 8Br-cGMP. 8-bromoguanosino-3',5'-cyclic monophosphorothioate glutathione S-transferase kappa 1 Homo sapiens