Title : Rosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse model.

Pub. Date : 2010 Apr

PMID : 19520921






1 Functional Relationships(s)
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1 Treatment with rosiglitazone prevented the development of pulmonary hypertension at 3 weeks; reversed established pulmonary hypertension at 5 weeks; and attenuated CH-stimulated Nox4 expression and superoxide production, PDGFRbeta activation, and reductions in PTEN expression. Rosiglitazone phosphatase and tensin homolog Mus musculus