Pub. Date : 2009 Jun
PMID : 19519318
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PI3K/Akt/JNK/c-Jun signaling pathway is a mediator for arsenite-induced cyclin D1 expression and cell growth in human bronchial epithelial cells. | arsenite | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | The inhibition of JNKs or c-Jun by chemical or genetic inhibitors blocks the cyclin D1 induction mediated by arsenite. | arsenite | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | Overall, our data suggest a pathway of PI-3K/Akt/JNK/c-Jun/cylin D1 signaling in response to arsenite in human bronchial epithelial cells. | arsenite | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |