Title : Genetic evidence for a predominant role of PI3Kbeta catalytic activity in ITAM- and integrin-mediated signaling in platelets.

Pub. Date : 2009 Sep 3

PMID : 19515725






1 Functional Relationships(s)
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1 We demonstrate that both isoforms were similarly required for maximal activation of the small GTPase Rap1b and for complete platelet aggregation upon stimulation of G protein-coupled receptors for adenosine 5"-diphosphate (ADP) or U46619. Adenosine Diphosphate RAS related protein 1b Mus musculus