Title : Synthetic triterpenoids attenuate cytotoxic retinal injury: cross-talk between Nrf2 and PI3K/AKT signaling through inhibition of the lipid phosphatase PTEN.

Pub. Date : 2009 Nov

PMID : 19494206






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CDDO-Bt directly binds cysteine 124 within PTEN"s active site and inhibits PTEN"s lipid phosphatase activity in vitro. Cysteine phosphatase and tensin homolog Mus musculus