Title : Genetic and environmental risks for high blood pressure among African American mothers and daughters.

Pub. Date : 2009 Jul

PMID : 19487301






3 Functional Relationships(s)
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1 RESULTS: Of the 4 single nucleotide polymorphisms (SNPs) on the sodium bicarbonate cotransporter gene (SLC4A5), rs8179526 had a statistically significant interaction with cytosine/thymine (C/T) genotype by sodium status on systolic BP (SBP; p=.0077). Sodium selenium binding protein 1 Homo sapiens
2 DISCUSSION: A gene x environmental interaction with rs8179526 has a protective effect on SBP in African-American women with high sodium intake. Sodium selenium binding protein 1 Homo sapiens
3 Participants with C/T genotype of rs8179526 who consumed greater than 2,300 mg of sodium had lower SBP than those who consumed less than recommended. Sodium selenium binding protein 1 Homo sapiens