Title : Estrogen receptor alpha, fos-related antigen-2, and c-Jun coordinately regulate human UDP glucuronosyltransferase 2B15 and 2B17 expression in response to 17beta-estradiol in MCF-7 cells.

Pub. Date : 2009 Aug

PMID : 19487245






2 Functional Relationships(s)
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1 Because UGT2B15 and UGT2B17 inactivate steroid hormones by glucuronidation, the regulation of their genes by 17beta-estradiol may maintain steroid hormone homeostasis and prevent excessive estrogen signaling activity. Steroids UDP glucuronosyltransferase family 2 member B17 Homo sapiens
2 Because UGT2B15 and UGT2B17 inactivate steroid hormones by glucuronidation, the regulation of their genes by 17beta-estradiol may maintain steroid hormone homeostasis and prevent excessive estrogen signaling activity. Steroids UDP glucuronosyltransferase family 2 member B17 Homo sapiens