Title : Periadventitial adipose tissue impairs coronary endothelial function via PKC-beta-dependent phosphorylation of nitric oxide synthase.

Pub. Date : 2009 Jul

PMID : 19482966






1 Functional Relationships(s)
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1 The selective inhibition of endothelial PKC-beta with ruboxistaurin (1 microM) abolished the adipose-induced impairment of bradykinin-mediated coronary vasodilation and the endothelial production of nitric oxide. ruboxistaurin kininogen 1 Canis lupus familiaris