Title : Activity and interactions of liposomal antibiotics in presence of polyanions and sputum of patients with cystic fibrosis.

Pub. Date : 2009 May 28

PMID : 19479000






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 DNA/F-actin (125 to 1000 mg/L) and LPS/LTA (1 to 1000 mg/L) inhibited conventional tobramycin bioactivity, whereas, liposome-entrapped tobramycin was inhibited at higher concentrations--DNA/F-actin (500 to 1000 mg/L) and LPS/LTA (100 to 1000 mg/L). Tobramycin interferon regulatory factor 6 Homo sapiens
2 DNA/F-actin (125 to 1000 mg/L) and LPS/LTA (1 to 1000 mg/L) inhibited conventional tobramycin bioactivity, whereas, liposome-entrapped tobramycin was inhibited at higher concentrations--DNA/F-actin (500 to 1000 mg/L) and LPS/LTA (100 to 1000 mg/L). Tobramycin interferon regulatory factor 6 Homo sapiens