Title : Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.

Pub. Date : 2009 Aug

PMID : 19478237






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In presence of inosine, AsV and DTT, PNP mediates AsIII formation. Inosine purine nucleoside phosphorylase Homo sapiens
2 In this study, we incubated PNP first with inosine and AsV, allowing the arsenolytic reaction to run, then blocked this reaction with the PNP inhibitor BCX-1777, added DTT and continued the incubation. Inosine purine nucleoside phosphorylase Homo sapiens