Title : Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia.

Pub. Date : 2009 May 27

PMID : 19474327






1 Functional Relationships(s)
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1 Our study demonstrates that STAT3 is a novel transcription factor of the mouse Mn-SOD gene and plays a crucial role as a neuroprotectant in regulating levels of reactive oxygen species in the mouse brain. Reactive Oxygen Species signal transducer and activator of transcription 3 Mus musculus