Title : Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design.

Pub. Date : 2009 Jul

PMID : 19472269






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Peptides that inhibit cyclin-dependent kinase 2 by blocking the macromolecular substrate recruitment site of cyclin A were simplified, for example, by replacement of dipeptide units with beta-amino acids. Dipeptides cyclin A2 Homo sapiens