Title : A covalent peptide inhibitor of RGS4 identified in a focused one-bead, one compound library screen.

Pub. Date : 2009 May 22

PMID : 19463173






1 Functional Relationships(s)
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1 RESULTS: Peptide 5nd (Tyr-Trp-c [Cys-Lys-Gly-Leu-Cys]-Lys-NH2, S-S) blocks the RGS4-Galphao interaction with an IC50 of 28 microM. Leu-Cys G protein subunit alpha o1 Homo sapiens