Title : Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress.

Pub. Date : 2009 Jul

PMID : 19457074






4 Functional Relationships(s)
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1 Analysis by non-reducing and reducing sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis/western blot of PFO-solubilized occludin revealed that occludin oligomeric assemblies co-localizing with "TJ-associated" raft domains contained a high molecular weight "structural core" that was resistant to disassembly by either SDS or a hydrophilic reducing agent ex vivo, and by Hx and H/R conditions in vivo. Sodium Dodecyl Sulfate occludin Rattus norvegicus
2 Analysis by non-reducing and reducing sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis/western blot of PFO-solubilized occludin revealed that occludin oligomeric assemblies co-localizing with "TJ-associated" raft domains contained a high molecular weight "structural core" that was resistant to disassembly by either SDS or a hydrophilic reducing agent ex vivo, and by Hx and H/R conditions in vivo. Sodium Dodecyl Sulfate occludin Rattus norvegicus
3 Analysis by non-reducing and reducing sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis/western blot of PFO-solubilized occludin revealed that occludin oligomeric assemblies co-localizing with "TJ-associated" raft domains contained a high molecular weight "structural core" that was resistant to disassembly by either SDS or a hydrophilic reducing agent ex vivo, and by Hx and H/R conditions in vivo. Sodium Dodecyl Sulfate occludin Rattus norvegicus
4 Analysis by non-reducing and reducing sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis/western blot of PFO-solubilized occludin revealed that occludin oligomeric assemblies co-localizing with "TJ-associated" raft domains contained a high molecular weight "structural core" that was resistant to disassembly by either SDS or a hydrophilic reducing agent ex vivo, and by Hx and H/R conditions in vivo. Sodium Dodecyl Sulfate occludin Rattus norvegicus