Title : Antihyperglycemic effects of total flavonoids from Polygonatum odoratum in STZ and alloxan-induced diabetic rats.

Pub. Date : 2009 Jul 30

PMID : 19454312






3 Functional Relationships(s)
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1 AIM OF THE STUDY: Total flavonids of Polygonatum(P) odoratum (TFP) were tested for anti-diabetic activity in streptozotocin (STZ)-induced diabetic mice and alloxan-induced diabetic rats. Alloxan tripartite motif-containing 39 Mus musculus
2 The experiments were designed to detect the anti-diabetic activity of TFP by determination of blood glucose (BG) using one touch gluco-meter and insulin levels by using a radioimmunoassay kit in streptozotocin (STZ)-induced diabetic mice and alloxan-induced diabetic rats and alpha-amylase inhibitory activity by alpha-amylase inhibition assay in vitro. Alloxan tripartite motif-containing 39 Mus musculus
3 TFP also could increase significantly the insulin level in alloxan-induced type 2 diabetic rats (P<0.05) compared with control. Alloxan tripartite motif-containing 39 Mus musculus