Title : CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.

Pub. Date : 2009 Jul 16

PMID : 19451552






1 Functional Relationships(s)
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1 Conversely, deficiency in the Rac guanine exchange factor DOCK2 significantly impaired CCL21-mediated costimulation in TCR-tg CD4(+) T cells, concomitant with impaired Rac- but not Ras-GTP formation. Guanosine Triphosphate AKT serine/threonine kinase 1 Homo sapiens