Pub. Date : 2009 Jun 18
PMID : 19449818
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oximes have been used as reactivators for organophosphorus-inhibited acetylcholinesterase (AChE). | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | We have concluded that oximes reactivate AChE by a three-step mechanism in opposition to the four-step processes of the other modeled nucleophiles. | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | In addition, our model suggests that oximes react with AChE in the deprotonated form (oximate). | Oximes | acetylcholinesterase (Cartwright blood group) | Homo sapiens |