Title : Resistin induces insulin resistance by both AMPK-dependent and AMPK-independent mechanisms in HepG2 cells.

Pub. Date : 2009 Aug

PMID : 19440859






2 Functional Relationships(s)
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1 This study investigated the effect of resistin on glucose metabolism and insulin signaling using human recombinant resistin and small interfering RNA (siRNA) against AMPKalpha2 to treat the human liver HepG2 cells. Glucose resistin Homo sapiens
2 Resistin also increases glucose production via AMPK-mediated upregulated expression of the genes encoding hepatic gluconeogenic enzymes, G6Pase, and PEPCK. Glucose resistin Homo sapiens