Title : A role of Gab2 association in Flt3 ITD mediated Stat5 phosphorylation and cell survival.

Pub. Date : 2009 Jul

PMID : 19438505






1 Functional Relationships(s)
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1 In this study, we identified tyrosines 768, 955 and 969 of Flt3 as phosphorylation sites and mediators of growth factor receptor binding protein 2 (Grb2) interaction, leading to the association of Grb2 associated binder 2 (Gab2) and contributing to proliferation and survival. Tyrosine FMS-like tyrosine kinase 3 Mus musculus