Title : GoLoco motif proteins binding to Galpha(i1): insights from molecular simulations.

Pub. Date : 2009 Dec

PMID : 19437048






2 Functional Relationships(s)
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1 Using these methodologies, binding of the GoLoco motif peptide to the Galpha(i1) subunit was found to restrict the relative movement of the helical and catalytic domains in the Galpha(i1) subunit, which is in agreement with a proposed mechanism of GDP dissociation inhibition by GoLoco motif proteins. Guanosine Diphosphate protein phosphatase 1 regulatory inhibitor subunit 1A Homo sapiens
2 Using these methodologies, binding of the GoLoco motif peptide to the Galpha(i1) subunit was found to restrict the relative movement of the helical and catalytic domains in the Galpha(i1) subunit, which is in agreement with a proposed mechanism of GDP dissociation inhibition by GoLoco motif proteins. Guanosine Diphosphate protein phosphatase 1 regulatory inhibitor subunit 1A Homo sapiens