Title : Development and pharmacologic characterization of deoxybromophospha sugar derivatives with antileukemic activity.

Pub. Date : 2010 Aug

PMID : 19436953






1 Functional Relationships(s)
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1 TMPP treatment effected a reduction in both cell cycle progression signals (FoxM1, KIS, Cdc25B, Cyclin D1, Cyclin A, and Aurora-B) and tumor cell survival (p27(Kip1) and p21(Cip1)), as well as induced the activation of caspase-3 and -9. 2,3,4-tribromo-3-methyl-1-phenylphospholane 1-oxide cyclin A2 Homo sapiens