Pub. Date : 2008 Nov-Dec
PMID : 19434858
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Targeted disruption of peptide transporter Pept1 gene in mice significantly reduces dipeptide absorption in intestine. | Dipeptides | solute carrier family 15 (oligopeptide transporter), member 1 | Mus musculus |
| 2 | Nevertheless, Pept1 deletion dramatically reduced the intestinal uptake and effective permeability of the model dipeptide GlySar (i.e., by at least 80%), and its oral absorption following gastric gavage (i.e., by about 50%). | Dipeptides | solute carrier family 15 (oligopeptide transporter), member 1 | Mus musculus |
| 3 | These novel findings provide strong evidence that PEPT1 has a major role in the in vivo oral absorption of dipeptides. | Dipeptides | solute carrier family 15 (oligopeptide transporter), member 1 | Mus musculus |