Pub. Date : 2009 May 8
PMID : 19429109
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mood stabilizing drugs lamotrigine and olanzapine increase expression and activity of glutathione S-transferase in primary cultured rat cerebral cortical cells. | Lamotrigine | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 2 | The purpose of the present study is to determine whether lamotrigine and olanzapine also regulate GST-M1. | Lamotrigine | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 3 | Using immunoblotting analysis and spectrophotometric assay, we examined the effect of lamotrigine or olanzapine on GST-M1 protein levels and GST enzyme activity in primary cultured rat cerebral cortical cells. | Lamotrigine | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 4 | We found that chronic treatment with lamotrigine or olanzapine increased both GST-M1 protein levels and GST enzyme activity. | Lamotrigine | hematopoietic prostaglandin D synthase | Rattus norvegicus |