Title : Tolerance to sedative/hypnotic actions of GABAergic drugs correlates with tolerance to potentiation of extrasynaptic tonic currents of alcohol-dependent rats.

Pub. Date : 2009 Jul

PMID : 19420124






1 Functional Relationships(s)
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1 Typical of several drug classes and two cell types, in CA1 pyramidal neurons, the benzodiazepine diazepam doubled the total charge transfer (TCT) of miniature postsynaptic inhibitory currents (mIPSCs), whereas it quadrupled the TCT of tonic currents. Diazepam carbonic anhydrase 1 Rattus norvegicus