Pub. Date : 2009 May 15
PMID : 19417138
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We show that induction of autophagy by Bortezomib is dependent on the proteasomal stabilisation of ATF4 and up-regulation of LC3B by ATF4. | Bortezomib | microtubule associated protein 1 light chain 3 beta | Homo sapiens |
2 | We show that ATF4 and LC3B play a critical role in activating autophagy and protecting cells from Bortezomib-induced cell death. | Bortezomib | microtubule associated protein 1 light chain 3 beta | Homo sapiens |