Title : Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation.

Pub. Date : 2009 May

PMID : 19384567






1 Functional Relationships(s)
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1 Ghrelin prevents MPTP-induced microglial activation in the SNpc and striatum, the expression of pro-inflammatory molecules tumor necrosis factor alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and the activation of inducible nitric oxide synthase. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine interleukin 1 beta Mus musculus