Title : Analysis of the functional role of Toll-like receptor-4 tyrosine phosphorylation.

Pub. Date : 2009

PMID : 19378035






1 Functional Relationships(s)
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1 Since posttranslational modifications of many receptor systems are important in initiating signaling, we studied whether tyrosine phosphorylation of TLR4, the principal sensor of Gram-negative bacterial lipopolysaccharide (LPS) plays a role in TLR4 signal-transducing functions. gram-negative bacterial lipopolysaccharide toll like receptor 4 Homo sapiens