Title : 1,4-Diamino-2,3-dicyano-1,4-bis(methylthio)butadiene (U0126) enhances the cytotoxicity of combretastatin A4 independently of mitogen-activated protein kinase kinase.

Pub. Date : 2009 Jul

PMID : 19377096






1 Functional Relationships(s)
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1 Combretastatin A4 (CA4) is a novel vascular-disrupting agent that has shown promising anticancer effects through its inhibition of microtubule assembly and subsequent disruption of tumor blood flow. fosbretabulin carbonic anhydrase 4 Homo sapiens