Title : Defective engraftment of C3aR-/- hematopoietic stem progenitor cells shows a novel role of the C3a-C3aR axis in bone marrow homing.

Pub. Date : 2009 Aug

PMID : 19357704






1 Functional Relationships(s)
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1 In agreement with the murine data, blockage of C3aR on human umbilical cord blood CD34(+) cells by C3aR antagonist SB290157 impairs their engraftment in non-obese diabetic/severe combined immunodeficient mice. SB 290157 CD34 molecule Homo sapiens