Title : Celastrol binds to ERK and inhibits FcepsilonRI signaling to exert an anti-allergic effect.

Pub. Date : 2009 Jun 10

PMID : 19356729






1 Functional Relationships(s)
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1 Celastrol decreased the secretion of beta-hexosaminidase, decreased the release of histamine, decreased the expression of Th2 cytokines and decreased calcium influx and cell adhesion in antigen-stimulated RBL2H3 cells. celastrol O-GlcNAcase Rattus norvegicus