Title : Kujin suppresses histamine signaling at the transcriptional level in toluene 2,4-diisocyanate-sensitized rats.

Pub. Date : 2009 Apr

PMID : 19352071






1 Functional Relationships(s)
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1 These data suggest that oral administration of Kujin showed anti-allergic activity through suppression of histamine signaling by the inhibition of TDI-induced H1R and HDC mRNA elevations followed by decrease in H1R, HDC protein level, and histamine content in the nasal mucosa of TDI-sensitized rats. Histamine histamine receptor H 1 Rattus norvegicus