Title : Fructose-1,6-bisphosphatase inhibitors. 1. Purine phosphonic acids as novel AMP mimics.

Pub. Date : 2009 May 14

PMID : 19348494






1 Functional Relationships(s)
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1 Herein we report the discovery of a series of purine phosphonic acids as AMP mimics targeting the AMP site of FBPase, which was achieved using a structure-guided drug design approach. Phosphorous Acids fructose-bisphosphatase 2 Rattus norvegicus