Title : Chronic production of peroxynitrite in the vascular wall impairs vasorelaxation function in SHR/NDmcr-cp rats, an animal model of metabolic syndrome.

Pub. Date : 2009 Apr

PMID : 19346675






1 Functional Relationships(s)
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1 Long-term (8 weeks) administration of telmisartan, an angiotensin II type 1-receptor antagonist, prevented the impaired vasorelaxation, decreased sGC expression and increased nitrotyrosine content in mesenteric arteries. Telmisartan guanylate cyclase 1 soluble subunit beta 2 Rattus norvegicus