Title : Acrolein, a ubiquitous pollutant and lipid hydroperoxide product, inhibits antiviral activity of interferon-alpha: relevance to hepatitis C.

Pub. Date : 2009 Jul 1

PMID : 19345260






1 Functional Relationships(s)
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1 Our data demonstrate that nontoxic concentrations of acrolein significantly inhibited IFNalpha-induced tyrosine phosphorylation of both cytoplasmic and nuclear STAT1 and STAT2, without altering the total levels. Tyrosine interferon alpha 1 Homo sapiens