Title : The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers.

Pub. Date : 2009 May 1

PMID : 19342873






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 However, P-gp contain many aspartate residues which could be targeted by caspases other than caspase-3. Aspartic Acid caspase 3 Homo sapiens