Title : An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity.

Pub. Date : 2009 Jul

PMID : 19337030






1 Functional Relationships(s)
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1 Further autophagy induction with rapamycin protects DA neurons from lactacystin-mediated cell death by downregulating p53 and its related apoptotic pathways and by inducing autophagy to degrade aggregated proteins. Sirolimus tumor protein p53 Homo sapiens