Title : Protein kinase C is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in human bladder cancer cells.

Pub. Date : 2009

PMID : 19322013






1 Functional Relationships(s)
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1 RESULTS: ATO inhibited proliferation and induced apoptosis of T24 cells in a dose-dependent manner, caused an increase of percentage of cells in the G(1) phase and a decrease in the S and G(2) phases, and upregulated the expression of activated caspase-3 and reduced PKC activity. Arsenic Trioxide caspase 3 Homo sapiens