Title : Na+/H+ exchangers and RhoA regulate acidic extracellular pH-induced lysosome trafficking in prostate cancer cells.

Pub. Date : 2009 Jun

PMID : 19302267






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Acidic pHe induced a cytoplasmic acidification (although cytoplasmic acidification was not sufficient for acidic pHe-induced lysosome trafficking and exocytosis) and inhibition of NHE activity with the amiloride derivative, EIPA or the anti-diabetic agent troglitazone prevented lysosome trafficking to the cell periphery. Amiloride solute carrier family 9 member C1 Homo sapiens