Title : Molecular cloning and oxidative modification of human lens ALDH1A1: implication in impaired detoxification of lipid aldehydes.

Pub. Date : 2009

PMID : 19296407






1 Functional Relationships(s)
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1 Citral, disulfiram, and cyanamide were found to inhibit human lens ALDH1A1 at IC50 values of 55, 101, and 22610 microM, respectively, whereas diethylstilbestrol (DES) was found to be an activator (EC(50), 1.3 microM). Disulfiram aldehyde dehydrogenase 1 family member A1 Homo sapiens