Title : Protein kinase D mediates mitogenic signaling by Gq-coupled receptors through protein kinase C-independent regulation of activation loop Ser744 and Ser748 phosphorylation.

Pub. Date : 2009 May 15

PMID : 19289471






1 Functional Relationships(s)
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1 Cell treatment with the preferential PKC inhibitors GF109203X or Go6983 profoundly inhibited PKD activation induced by bombesin stimulation for <15 min but did not prevent PKD catalytic activation induced by bombesin stimulation for longer times (>60 min). bisindolylmaleimide I protein kinase D1 Mus musculus