Pub. Date : 2009 May 1
PMID : 19285975
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake. | Nicotine | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 2 | Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake. | Nicotine | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 3 | CYP2B1/2 proteins were not induced by nicotine alone, but were increased by 2.2-2.5 fold by ethanol drinking (P<0.05). | Nicotine | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |
| 4 | Chronic nicotine increased voluntary ethanol intake thereby enhancing CYP2E1 and CYP2B1/2 levels. | Nicotine | cytochrome P450, family 2, subfamily b, polypeptide 1 | Rattus norvegicus |