Title : Expression, purification and in vitro functional reconstitution of the chemokine receptor CCR1.

Pub. Date : 2009 Jul

PMID : 19275940






1 Functional Relationships(s)
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1 A strict dependence of function on the detergent composition was observed, as solubilization of CCR1 in n-dodecyl-beta-D-maltopyranoside/cholesteryl hemisuccinate yielded functional receptor with a K(d) of 21 nM for the chemokine CCL14, whereas it was non-functional in phosphocholine detergents. dodecyl maltopyranoside C-C motif chemokine ligand 14 Homo sapiens