Title : Overexpression of mitochondrial ferritin sensitizes cells to oxidative stress via an iron-mediated mechanism.

Pub. Date : 2009 Aug

PMID : 19271990






2 Functional Relationships(s)
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1 Moreover, mechanistic studies demonstrated that tBHP treatment led to a prolonged decrease in cytosolic ferritins levels in MtFt-expressing cells, while ferritin levels recovered to basal levels in control counterparts. tert-Butylhydroperoxide ferritin mitochondrial Homo sapiens
2 tBHP treatment also resulted in elevated transferrin receptors, followed by more iron acquisition in MtFt expressing cells. tert-Butylhydroperoxide ferritin mitochondrial Homo sapiens