Title : Antiviral activity of carbohydrate-binding agents and the role of DC-SIGN in dengue virus infection.

Pub. Date : 2009 Apr 25

PMID : 19264337






1 Functional Relationships(s)
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1 Several carbohydrate-binding agents (CBAs), such as the plant lectins HHA, GNA (mannose-specific) and UDA (N-acetylglucosamine-specific), inhibited dose-dependently the binding of DENV and subsequently viral replication in Raji/DC-SIGN(+) cells (EC(50): 0.1-2.2 microM). Carbohydrates CD209 molecule Homo sapiens