Pub. Date : 2008 Dec
PMID : 19259045
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The main objectives of this study were to determine the role of recombinant human erythropoietin (Epoetin alfa) in the prevention of nephrotoxicity induced experimentally in Wistar rats by long-term administration of cisplatin (2 mg/kg/b.w./week) over eight weeks, and an evaluation of its effect on renal tubular cell proliferation. | Cisplatin | erythropoietin | Homo sapiens |
2 | The main objectives of this study were to determine the role of recombinant human erythropoietin (Epoetin alfa) in the prevention of nephrotoxicity induced experimentally in Wistar rats by long-term administration of cisplatin (2 mg/kg/b.w./week) over eight weeks, and an evaluation of its effect on renal tubular cell proliferation. | Cisplatin | erythropoietin | Homo sapiens |
3 | The results obtained have shown that epoetin alfa significantly reduced the functional renal failures and renal damages, and increased toleration of high doses of cisplatin. | Cisplatin | erythropoietin | Homo sapiens |