Title : A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease.

Pub. Date : 2009 Jun

PMID : 19250966






3 Functional Relationships(s)
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1 A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson"s disease. Iron transferrin receptor 2 Homo sapiens
2 Here, we report a novel transferrin/transferrin receptor 2 (Tf/TfR2)-mediated iron transport pathway in mitochondria of SN dopamine neurons. Iron transferrin receptor 2 Homo sapiens
3 Importantly, the Tf/TfR2 pathway can deliver Tf bound iron to mitochondria and to the respiratory complex I as well. Iron transferrin receptor 2 Homo sapiens