Title : Tunicamycin suppresses cisplatin-induced HepG2 cell apoptosis via enhancing p53 protein nuclear export.

Pub. Date : 2009 Jul

PMID : 19242657






2 Functional Relationships(s)
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1 Tunicamycin suppresses cisplatin-induced HepG2 cell apoptosis via enhancing p53 protein nuclear export. Tunicamycin tumor protein p53 Homo sapiens
2 In order to further explore the mechanism underlying tumor resistance to cisplatin, we observed that increased nuclear export of endogenous p53 protein by pharmacological inducers of ER stress, such as tunicamycin, was associated with the suppression of cisplatin-induced apoptosis. Tunicamycin tumor protein p53 Homo sapiens