Title : Bisphosphonate zoledronic acid enhances the inhibitory effects of gefitinib on EGFR-mutated non-small cell lung carcinoma cells.

Pub. Date : 2009 Jun 8

PMID : 19233551






1 Functional Relationships(s)
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1 Gefitinib suppressed EGF-activated phosphorylation of ERK1/2 and Akt, while zoledronate seemed to impose its pharmacological effect independent of ERK1/2 and Akt phosphorylation. Gefitinib AKT serine/threonine kinase 1 Homo sapiens